ADL OncoMut™ Focus Screen

ADL OncoMut™ Focus Screen

Oncology

Regulatory Status: LDT

The ADL OncoMut Focus Screen is an amplicon-sequencing assay designed to detect single nucleotide variants (SNVs) and deletions in FFPE samples.

15 samples are batched in each run, with median coverage >500x, allowing mutation detection sensitivity of 5-10%.

TARGET GENES 

31 genes, >100 amplicons, >300 mutations
AKT1 FBXW7 NOTCH1
ALK FGFR1 NRAS
APC FGFR2 PIK3CA
BRAF FGFR3 PTEN*
c-KIT CDKN2A GNAS
CTNNB1 KRAS RET
DDR2 MAP2K1 ROS1
EGFR MAP3K1 SMAD4
ERBB2 MET SMO
ERBB4 MTOR STK11*
TP53*

*Hotspot